CBD is one of the natural cannabinoids found strictly in the cannabis plant. CBD is non-psychotropic, meaning it does not cause the intoxicating effects for which THC, the illegal cannabinoid, is known.
And products containing cannabidiol (CBD) have become increasingly popular in recent years And it’s not hard to understand why, because this natural compound can provide benefits for an extremely wide range of symptoms and disorders.
Cannabidiol acts mainly by interacting with our body’s endocannabinoid system (SE) and through another complex chemical system of “second messenger” in the brain and body, which maintains a healthy state of balance, called homeostasis, by regulating major processes, such as mood, mood, and mood. pain, brain function and metabolism.
So far, research has shown how CBD and other cannabinoids have the potential to help in a wide range of conditions, from anxiety to epilepsy or difficult-to-treat symptoms such as chronic pain.
In this article, we present in more detail 15 of the scientific evidence-based benefits of CBD oil:
1. Anxiety and depression
Anxiety and depression are the most common mental health disorders globally. There is scientific evidence showing how CBD may be able to help with anxiety, and so far, in scientific tests performed on animals, CBD has been shown to have antidepressant properties, although no direct clinical trials have yet been performed in humans. However, certain strains of cannabis have been shown to help with depression and mixed anxiety/depression in clinical practice.
Researchers believe CBD may be useful for various types of anxiety disorders, including generalized anxiety disorder, post-traumatic stress disorder (PTSD), and obsessive-compulsive disorder.
One study found that, unlike placebo, a 600 mg dose of pure CBD improved public speaking anxiety in people with social anxiety disorder. Similarly, a 2019 study in Japan reported that CBD oil decreased anxiety in adolescents with sad, while a placebo had no effect.
Evidence from studies also suggests that CBD may have antidepressant effects. A case report of a young woman suffering from anxiety and depression related to substance abuse found that CBD treatment improved “depressive as well as anxiety symptoms.” Researchers believe that CBD produces its antidepressant and anxiety-relieving effects by interacting with THE SE, as well as with serotonin receptors and the neurotransmitter GABA (brain chemical).
2. Pain and inflammation
Pain and inflammation can manifest in many ways, such as pain after exercise or chronic pain associated with numerous conditions, including cancer, multiple sclerosis, and arthritis.
Cannabis has been used as a pain reliever for centuries, and chronic pain remains the most common health condition that qualifies for medical cannabis use. Because CBD is a significant component of cannabis, it is not surprising that it possesses pain-relieving properties.
The effects of cannabidiol can relieve pain and inflammation in two ways. For starters, it can help regulate pain signals via SEVERAL signaling pathways. In addition, CBD interacts with several receptors that regulate pain and inflammation, such as TRPV1. An animal study found that a topical gel containing CBD relieved pain and inflammation in mice with arthritis. Similarly, a study on Sativex, a drug containing CBD and THC, reported chronic pain relief in people suffering from rheumatoid arthritis.
In other countries with more contemporary legislation, patients using « medical » cannabis also found it helpful in the case of pain related to autoimmune arthritis and other similar conditions through various varieties of hemp with a high content of CBD. Sativex also alleviated pain in another study in people with multiple sclerosis. Meanwhile, a study in Uruguay found that CBD reduced pain after kidney transplantation in elderly patients.
An even more promising 2020 study looked at whether full spectrum CBD cannabis oil can help people suffering from chronic pain to reduce the use of prescription opioid painkillers. A total of 97 patients used CBD oil for 8 weeks, along with their standard medications. By the end of the study, more than half of the participants had reduced or completely stopped using opioids, and 94% of them said CBD improved their quality of life, especially in the study.
In conclusion, available evidence suggests that CBD has strong anti-inflammatory properties and can relieve various types of pain, especially when used in combination with THC. In addition, CBD also helps with the anxiety experienced by those suffering from chronic pain because of the effects of chronic pain in brain regions related to stress, mood and anxiety.
3. Sleep
Insomnia and other sleep disorders are among the most common health problems in the world, and even in this case, CBD can provide some help.
In one study, adults with anxiety or sleep problems were given CBD capsules daily for 3 months. In the first month, 79% noticed a reduction in anxiety and 67% had improved sleep as a side benefit. Another study found that CBD improved the symptoms of REM sleep behavior disorder. There is also evidence that cannabidiol can help with restless leg syndrome, which makes it difficult to sleep by causing the need to move the legs at night.
Researchers are not entirely sure how CBD directly helps sleep, but one of the most common reasons for restless or poor sleep, which leads to daytime fatigue and reduced quality of life, is due to stress and anxiety. And the fact that CBD can reduce stress and anxiety is recognized and possibly affect the levels of stress hormones, all of which remove the barriers that stand in the way of healthy sleep.
CBD can also directly influence certain aspects of sleep through its effects on various brain neurotransmitters, such as serotonin and GABA, one of the calming brain chemicals, but we do not yet know the exact mechanism. The pain-relieving and inflammation-relieving effects could also be helpful, as these problems can keep you awake at night.
4. Neuroprotection
Neurodegenerative conditions such as Alzheimer’s, Parkinson’s and Huntington’s disease are some of the hardest to treat What they have in common is damage to the function and structure of neurons. Several studies have shown that CBD also has neuroprotective properties.
In an animal study, CBD reversed or prevented thinking problems associated with cognitive decline. A similar study found that CBD counteracted the development of memory problems that occurred with Alzheimer’s disease.
Meanwhile, a promising 2019 study tested the effects of cannabis oil containing a 2:1 ratio of CBD to THC in people with severe dementia. The treatment not only improved the patients’ behavior, but also reduced their daily care needs. Also, half of the participants were able to reduce or completely stop taking other prescription drugs.
Similarly, positive results have been reported in Parkinson’s disease studies. In a clinical trial, doses of 300 mg of CBD improved the quality of life in people with Parkinson’s disease, while placebo had no effect. Another study found that CBD improved psychosis, a symptom in some forms of this disease.
5 the cancer
Cannabinoids are a new and exciting field of research in the field of cancer treatment. Currently, medical cannabis containing both CBD and varying amounts of THC may be useful to help improve quality of life, cancer symptoms and side effects of chemotherapy treatment when used under medical guidance.
One study looked at the effectiveness of THC alone or alongside CBD in patients with treatment-resistant, advanced-stage cancer pain. Only the CBD plus THC group experienced a reduction in pain, with 43% of patients reporting an improvement of 30% or more. A study in rats using CBD showed that it could have anti-emetic properties, just like THC, which are particularly useful for the side effects of chemotherapy. Although to date, strictly CBD has not been proven for this indication in humans, and medical cannabis containing THC is the cannabinoid treatment of choice for nausea and vomiting, along with CBD to alleviate the negative side effects of THC.
This was demonstrated by a study in which a synthetic version of THC alone improved chemotherapy-induced nausea in cancer patients. Meanwhile, an animal study found that CBD reduced neuropathic pain caused by the chemotherapy drug paclitaxel. CBD can also help with anxiety and sleep problems, which have an increased chance of occurring in cancer patients.
Another study found that CBD has chemopreventive effects that protected subjects from developing colon cancer.
In general, CBD seems to offer many benefits to cancer patients, especially when it is associated with THC (usually in some countries with modern legislation). However, preclinical evidence is not enough and more human studies are needed to confirm its direct cancer benefits, as different tumors have different responses to each cannabinoid and even at different doses can have opposite tumor effects. Even within a specific type of cancer, cannabinoid receptors on the tumor can have an impact on the potential anticancer effect of CBD and other cannabinoids, so we still have much to learn about how to direct specific cannabinoids to specific types of tumors.
6. CBD for multiple sclerosis
Multiple sclerosis (MS) is a chronic condition involving the body’s central nervous system, which causes inflammation, temporary injury and, in some cases, neuropathic pain. Acute neuropathic pain may be one of the first signs of multiple sclerosis or may be a sign of a relapse. There are some symptoms of multiple sclerosis that can be alleviated or helped by using CBD.
Some people choose to use CBD to manage chronic pain associated with MS. CBD has many health benefits, making it an attractive and useful option for people suffering from conditions like MS. Sativex, the first CBD-based drug, may be an effective treatment for this medical condition.
A clinical study found in Front Neurol in 2018 explains that products with a CBD:THC ratio of 1:1 could help greatly reduce pain, as well as muscle stiffness and stiffness associated with MS. Another therapeutic benefit of CBD oil is that it has natural anti-inflammatory properties that can help improve mobility and reduce the inflammation associated with fatigue in people suffering from MS.
The benefit of using CBD to help treat multiple sclerosis symptoms is that there is evidence from human studies.
7. Cardiovascular health
There is also emerging evidence that CBD has multiple beneficial effects on the health of the heart and other components of the cardiovascular system.
First, CBD can reduce high blood pressure, one of the key risk factors for stroke and other cardiovascular diseases. In one study, CBD lowered blood pressure at rest and reduced the increase in blood pressure associated with stressful situations.
CBD can also protect against atherosclerosis, the accumulation of plaque in artery walls. This was demonstrated in an in vitro study, in which CBD protected human coronary cells from damage caused by high blood sugar levels.
Studies have also shown that CBD may help with cardiomyopathy and other cardiovascular complications of diabetes in animals. But it also protects against stroke by increasing cerebral blood flow.
8 epilepsy
If there is a benefit of CBD that is supported by so much scientific evidence that it is recommended by doctors, it is relieving treatment-resistant forms of epilepsy.
The first and only pharmaceutical drug containing pure CBD, Epidiolex, was recently approved to treat convulsive disorders such as Dravet syndrome and Lennox-Gastaut syndrome, two rare and severe types of epilepsy that affect children. CBD as a treatment for epilepsy is promising, but requires additional systematic analysis before it can go beyond the anecdotal evidence.
In several randomized clinical trials, the gold standard in medical research, it was found that Epidiolex significantly reduced seizures in children suffering from these conditions. In addition to this, many other studies have also found that CBD helps with epilepsy.
A review of 36 studies reported that CBD not only reduces the number of seizures, but can even stop them completely in some people. Researchers believe that CBD works by interrupting the abnormal activity of the neurons that cause these seizures.
CBD can also protect against atherosclerosis, the accumulation of plaque in the artery walls. This was demonstrated in an in vitro study, in which CBD protected human coronary cells from damage caused by high blood sugar levels.
Studies have also shown that CBD can help with cardiomyopathy and other cardiovascular complications of diabetes in animals. But it also protects against stroke by increasing cerebral blood flow.
9. Skin health
THE ENDOCANNABINOID system (SE) is present throughout the body, including the skin, the largest organ in our body. It plays an essential role in skin health by regulating viral processes such as inflammation and cell growth. There is also evidence that dysfunction IS involved in many skin conditions, such as eczema, psoriasis and acne.
Therefore, CBD has a potential role to play in supporting skin health. A recent study looked at the effectiveness of a topical ointment with CBD infusion in people with psoriasis, eczema and scars from these and other inflammatory skin conditions. After 90 days, the study participants noticed improvements in skin elasticity and hydration, as well as psoriasis symptoms, scars, spots and other skin health measures.
Another study examined the effects of CBD on sebocytes, skin cells that produce sebum, the oily substance that plays the central role in acne. CBD reduced inflammation and suppressed the production of sebum and new sebocytes, leading researchers to conclude that “CBD has potential as a promising therapeutic agent for the treatment of acne vulgaris.”
10. Arthritis
Current studies show that CBD may have the ability to relieve pain and reduce inflammation, but this still needs to be validated through several clinical trials. However, many anecdotal reports from those who have tried CBD for arthritis have observed a reduction in pain and even an improvement in sleep.
Topical application of CBD has the potential to relieve pain and be an effective treatment for arthritis because it helps reduce inflammation. However, there is currently no scientific evidence to provide a conclusive answer to the fact that CBD can be an effective treatment for arthritis. If you treat arthritis with medication, it is not recommended to use CBD as a substitute for prescription drugs, but only complementary.
11. Digestive health
Early studies suggest that CBD may be beneficial for digestive symptoms such as nausea and abdominal pain, as well as for disorders such as inflammatory bowel disease.
In one such study, cannabis extract rich in CBD improved quality of life and symptoms in people with ulcerative colitis, one of the two main types of inflammatory bowel disease.
12. CBD for lupus
Lupus is an autoimmune condition that can usually be marked by an inflammation of the immune system that causes it to attack its own tissue. Currently, there is no cure for lupus, which makes finding treatments that help alleviate symptoms change the lives of people suffering from lupus.
CBD could help alleviate certain types of seizures to help relieve symptoms. Cannabidiol has remarkable anti-inflammatory properties and has no dangerous side effects, making it a suitable option for people with lupus. This is because CBD blocks the release of inflammatory proteins while interrupting pain signaling in the brain. This is because CBD interacts with TRPV1 cells.
The best type of CBD to try for lupus is full spectrum CBD, to benefit from the full range of cannabinoids found in the cannabis plant and the so-called “entourage effect” among them. Before trying CBD products for their therapeutic effects, always consult your doctor, as CBD may interact with certain medications prescribed to people with lupus.
13. Drug addiction
One of the most interesting areas of CBD research is the treatment of substance addiction. CBD has no addictive properties, and there is evidence that it can reduce the craving for many common drugs, including opioids and nicotine.
A study of 24 smokers tested whether CBD could help them quit smoking. They used an inhaler containing CBD or a placebo every day for a week. The CBD group smoked 40% fewer cigarettes during the study, and some smokers even maintained this reduction after the study. Meanwhile, studies in mice suggest that CBD can reduce cravings for alcohol and cocaine.
CBD can also help to stop THC-rich cannabis. A study of 94 marijuana users found that those who smoked certain varieties with a high content of CBD scored better when assessing cannabis addiction. Similarly, a case report of a woman suffering from anxiety, depression, insomnia and other symptoms of cannabis withdrawal syndrome reported that CBD led to a major improvement, and CBD may also be useful for opioid addiction.
A study of people addicted to heroin tested whether CBD can reduce the appetite for opioids. They took CBD for 3 days. While the placebo treatment had no effect, CBD significantly reduced the appetite for opioids, and the effects persisted for one week after the study. CBD is so promising that Yasmin Hurd, a neuroscientist and highly respected addiction researcher, believes it has a real potential to combat the opioid epidemic in the US, the widespread misuse of prescription and non-prescription opioid drugs. that leads to tens of thousands of overdose deaths each year.
14. Diabetes
Research shows that CBD can have a positive effect on type 1 diabetes and complications of diabetes, such as nerve damage.
Several studies in mice have shown that CBD can slow and prevent the development of type 1 diabetes, especially through its anti-inflammatory effects and a change in immune response to diabetes development and pancreatic cell destruction.
Animal research evidence also suggests that CBD may be beneficial for diabetes complications, including diabetic cardiomyopathy (heart muscle disorder), diabetic retinopathy (eye damage), diabetic neuropathy (a type of nerve damage).
15. Migraines
There is growing evidence that migraines and some other difficult-to-treat conditions are caused by a clinical endocannabinoid deficiency, i.e. insufficient endocannabinoid activity. Since we know that CBD appears to help by potentially modulating endocannabinoid levels in the body, this may suggest a mechanism by which it can relieve migraines.
However, clinical research evidence is needed to support this theory.
Side effects of CBD
CBD has the potential to be a natural chemical compound beneficial for health in many ways, but does it have potential side effects?
Fortunately, one of the reasons CBD is so popular is that it is extremely well tolerated by most people, especially at over-the-counter wellness doses used without the supervision of a doctor.
CBD can cause some side effects, they are generally quite rare and tend to be mild and temporary.
These potential risks and effects include dry mouth, dizziness, low blood pressure, fatigue, diarrhea, and changes in appetite or weight, but at the wellness doses used, they are very uncommon. In general, these effects were only observed by studies that used high doses of pure CBD (300 mg or more daily), much higher than the doses normally used.
Animal studies also suggest that CBD may also increase or increase the level of CBD. In some cases, reduce the effectiveness of certain prescription drugs and drugs by affecting the function of CYP450 liver enzymes, but most of these interactions are unpublished and are probably not clinically relevant.
However, certain types of medications may be at higher risk, so if you are taking medications, the safety recommendation is to consult your family doctor or specialist before trying CBD.
CBD has no addictive properties, does not cause withdrawal, and there is no evidence that it produces tolerance when used regularly for long periods of time.
Conclusion: 15 benefits of CBD
CBD has been extensively studied, suggesting it could have potential benefits for many common problems, such as anxiety, pain, inflammation, poor sleep, and a long list of chronic diseases and symptoms.
Although more high-quality research is needed on humans to confirm the benefits of CBD, available evidence suggests that it is a safe, no-side compound that provides a natural alternative to many common well-being problems.
There are many possible health benefits that can be offered by the cannabis plant. Products extracted from Cannabis sativa, such as CBD oil, have a lot to offer, and we will certainly soon see greater progress on medical cannabis (marijuana), perhaps even in Romania. It is always recommended…
Although more high-quality research is needed on humans to confirm the benefits of CBD, available evidence suggests that it is a safe, no-side compound that provides a natural alternative to many common well-being problems.
There are many possible health benefits that can be offered by the cannabis plant. Products extracted from Cannabis sativa, such as CBD oil, have a lot to offer, and we will certainly soon see greater progress on medical cannabis (marijuana), perhaps even in Romania. It is always recommended to consult your doctor before taking CBD for the first time, especially if you are already taking prescription drugs.
In case you want to try the best CBD products available today, you’ve come to the right place. Zen Float offers you a wide range of CBD oils, capsules, cosmetics, CBD products for dogs / cats, of the highest quality: Pure natural.